Abstract

Bisphenols are a group of compounds containing two hydroxyphenyl functional groups joined together by a differently substituted bridging atom. Bisphenol A (BPA) is the best known of the bisphenol analogues. BPA is commonly used as the base chemical in polycarbonate plastic production; and has been found to leach out of different products in both acidic and basic conditions and most environmental matrices. BPA is an endocrine disrupting chemical (EDC) and due to BPA’s toxic affects regulatory measures have been put into effect in an effort to limit the use of BPA. Commercialization of BPA-free products is increasing, with the substitution of BPA with its analogues. However, certain analogues have been shown to have nearly identical endocrine disrupting effects (BPS and BPF), while others cause increased concern due to their unstudied effects on health and the environment. The aim of this project is to optimize a method for the separation and identification of 13 bisphenol analogues (BPA, BPAF, BPB, BPBP, BPC, BPE, BPF, BPFL, BPG, BPM, BPP, BPS and BPZ) using the analytical technique of capillary electrophoresis (CE). This method can become a valuable resource in monitoring bisphenol contamination in food and the environment.

Department

Chemistry

Faculty Advisor

Kingsley Donkor

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Simultaneous Separation and Identification of Bisphenol Analogues by Capillary Electrophoresis

Bisphenols are a group of compounds containing two hydroxyphenyl functional groups joined together by a differently substituted bridging atom. Bisphenol A (BPA) is the best known of the bisphenol analogues. BPA is commonly used as the base chemical in polycarbonate plastic production; and has been found to leach out of different products in both acidic and basic conditions and most environmental matrices. BPA is an endocrine disrupting chemical (EDC) and due to BPA’s toxic affects regulatory measures have been put into effect in an effort to limit the use of BPA. Commercialization of BPA-free products is increasing, with the substitution of BPA with its analogues. However, certain analogues have been shown to have nearly identical endocrine disrupting effects (BPS and BPF), while others cause increased concern due to their unstudied effects on health and the environment. The aim of this project is to optimize a method for the separation and identification of 13 bisphenol analogues (BPA, BPAF, BPB, BPBP, BPC, BPE, BPF, BPFL, BPG, BPM, BPP, BPS and BPZ) using the analytical technique of capillary electrophoresis (CE). This method can become a valuable resource in monitoring bisphenol contamination in food and the environment.

 

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