Presentation Title

Development of Directed Lateral Lithiation Reactions for Use in Advanced Undergraduate Experiments

Format of Presentation

Poster to be presented the Friday of the conference

Abstract

Directed lithiation reactions involving aromatic compounds containing a “directing group” have become an essential method for the synthesis of a variety of aromatic compounds that are difficult to synthesize by other methods. Many of these compounds have found important applications in industry, especially in the synthesis of pharmaceutical drugs and technologically advanced materials such as liquid crystals. Our research involves the development of examples of the above named class of reactions suitable for use as organic synthesis projects at the advanced undergraduate laboratory level. A series of these reactions and the compounds synthesized will be described, along with detailed results of the characterization of the various compounds.

Department

Chemistry

Faculty Advisor

Norman Reed

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Development of Directed Lateral Lithiation Reactions for Use in Advanced Undergraduate Experiments

Directed lithiation reactions involving aromatic compounds containing a “directing group” have become an essential method for the synthesis of a variety of aromatic compounds that are difficult to synthesize by other methods. Many of these compounds have found important applications in industry, especially in the synthesis of pharmaceutical drugs and technologically advanced materials such as liquid crystals. Our research involves the development of examples of the above named class of reactions suitable for use as organic synthesis projects at the advanced undergraduate laboratory level. A series of these reactions and the compounds synthesized will be described, along with detailed results of the characterization of the various compounds.