Presentation Title

The Peaks of a Preservative: Quantification of Parabens in Cosmetic Foundation

Format of Presentation

15-minute lecture to be presented April 1, 2017

Location

IB 1015

Start Date

1-4-2017 2:00 PM

End Date

1-4-2017 2:15 PM

Abstract

Parabens are a large class of compounds that are found in personal care products, pharmaceuticals, and food because of their ability to act as a preservative. Unfortunately, the detection of parabens in human breast cancer tissue, urine, blood, and milk has sparked some concern. Consequently, there is a need to develop methods to quantify parabens in a variety of matrices such as cosmetic foundations. In this study, ethylparaben, butylparaben, propylparaben, and methylparaben were extracted from several cosmetic foundations using an adaptation from a previously used method. Liquid-chromatography mass-spectrometry was used to separate the parabens and quantify the amount present in the samples. External standard calibration was used to analyze the data and determine the concentrations present. Based on the results, it was possible to optimize and validate a method to quantify low concentrations of parabens in four different foundation samples.

Department

Chemistry

Faculty Advisor

Kingsley Donkor

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Apr 1st, 2:00 PM Apr 1st, 2:15 PM

The Peaks of a Preservative: Quantification of Parabens in Cosmetic Foundation

IB 1015

Parabens are a large class of compounds that are found in personal care products, pharmaceuticals, and food because of their ability to act as a preservative. Unfortunately, the detection of parabens in human breast cancer tissue, urine, blood, and milk has sparked some concern. Consequently, there is a need to develop methods to quantify parabens in a variety of matrices such as cosmetic foundations. In this study, ethylparaben, butylparaben, propylparaben, and methylparaben were extracted from several cosmetic foundations using an adaptation from a previously used method. Liquid-chromatography mass-spectrometry was used to separate the parabens and quantify the amount present in the samples. External standard calibration was used to analyze the data and determine the concentrations present. Based on the results, it was possible to optimize and validate a method to quantify low concentrations of parabens in four different foundation samples.