Presentation Title

Investigating Lifespan and Healthspan Effects of Canada-grown Lonicera caerulea on C. elegans

Format of Presentation

Poster to be presented Friday March 31, 2017

Abstract

Lifespan and healthspan studies have grown in popularity, especially in research surrounding health supplements suspected to have positive or negative effects on humans. While fruit such as Acai fruits have been suggested to increase healthspan and lifespan, rising price and the need for international import of these fruits may act as deterrent to widespread consumption. In this study, the effects of Canada grown Lonicera caerulea (haskap berry) on model organism C. elegans were investigated. Although investigations of anti-inflammatory and anti-oxidant effects of the haskap berry have been done, at this time there have been no general in vivo studies of lifespan and healthspan effects of the berry. Through lifespan, fecundity, oxidative stress, and heat stress assays under various concentrations of haskap berry extract, the general effects of the berry on C. elegans can be determined. After determination of the overall effects of the extract, C. elegans mutants can be tested to help determine the biological pathways resulting in the observed lifespan and healthspan effects. As an initial investigation into broad in vivo effects of the haskap berry, this study will provide both a methodological and a data-driven starting point for future research on the various varieties, effects, and applications of the haskap berry.

Department

Biological Sciences

Faculty Advisor

Nathan Bialas

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Investigating Lifespan and Healthspan Effects of Canada-grown Lonicera caerulea on C. elegans

Lifespan and healthspan studies have grown in popularity, especially in research surrounding health supplements suspected to have positive or negative effects on humans. While fruit such as Acai fruits have been suggested to increase healthspan and lifespan, rising price and the need for international import of these fruits may act as deterrent to widespread consumption. In this study, the effects of Canada grown Lonicera caerulea (haskap berry) on model organism C. elegans were investigated. Although investigations of anti-inflammatory and anti-oxidant effects of the haskap berry have been done, at this time there have been no general in vivo studies of lifespan and healthspan effects of the berry. Through lifespan, fecundity, oxidative stress, and heat stress assays under various concentrations of haskap berry extract, the general effects of the berry on C. elegans can be determined. After determination of the overall effects of the extract, C. elegans mutants can be tested to help determine the biological pathways resulting in the observed lifespan and healthspan effects. As an initial investigation into broad in vivo effects of the haskap berry, this study will provide both a methodological and a data-driven starting point for future research on the various varieties, effects, and applications of the haskap berry.